COVID-19

3rd dose of the Covid vaccine: is the health pass withdrawn in case of refusal? Pfizer 96% effective …

3rd DOSE. While the government evokes the “possibility” of withdrawing the health pass in case of rejection of the 3rd dose. Pfizer says its vaccine is 96% effective.

Summary

[Mis à jour le 21 octobre 2021 à 15h34] Latest information. While the Moderna vaccine “has not been recommended” for the Covid booster dose, its counterpart Pfizer has revealed very promising results from its Phase 3 clinical trial on the third dose. According to the scientists’ conclusions, a third dose would be 95.6% effective against symptomatic forms of the disease. “The phase 3 clinical trial, conducted in 10,000 people over the age of 16, shows” a relative efficacy of 95.6% and a favorable safety profile, “according to a press release.” These results once again demonstrate the usefulness of reminders in our efforts to protect the public against this disease, ”explained Albert Bourla, CEO of Pfizer.

In addition, after the obligation to vaccinate the caregivers, after the obligation to vaccinate the health pass, will the latter be excluded in the event of rejection of the 3rd dose? For now, the government has yet to make up its mind. Guest of RTL this Tuesday, October 19, Gabriel Attal, government spokesman, confirmed the “possibility” of such a measure but assures “that no decision has been made in this regard today.” Words that confirm those of Jean Castex on Monday at noon in the Vatican. The Prime Minister, questioned on the matter, explained that the decision was submitted to the HAS and the Scientific Council. “The conditions to benefit from the pass are established by the HAS (Haute Autorité de Santé). Is it up to the HAS to tell us whether or not we should extend the eligibility of the pass to the third dose? Opinion is requested.” Asked again about this issue, Matignon postponed with BFM TV “the question of suspending the vaccination pass for a third dose will be submitted to arbitration by the President of the Republic and the Prime Minister. Then, if validated, it will require an opinion from the HAS and the Scientific Council “.

In addition, a few days ago, the High Health Authority “advised against” the use of Moderna vaccine as a booster dose. To justify this decision, the HAS relied on a Scandinavian study that should appear in the next few days on the risk of myocarditis in people under 30 years of age. Announcements from various health authorities have highlighted the remaining unknowns about the dose and target population for withdrawal by Spikevax (Moderna vaccine, editor’s note) and justify waiting for the European body to provide the expected details in the context of marketing. authorization under examination “.

New government tightening in the vaccination campaign? According to the Minister of Labor Elisabeth Borne interviewed by Europa 1, the withdrawal of the health pass could be registered in the event of rejection of the 3rd dose. “It is something that we are seeing but it is not decided today,” he said on Friday, October 15. “We know that immunity drops dramatically after six months, so it is absolutely necessary to administer this third dose.” In early September, theThe Ministry of Health provided Information what a “The person eligible for a booster dose will retain a valid 2/2 pass. If the person takes a third dose, they will have a new pass marked 3/3. But the old one will still be valid. “

From May 5, immunosuppressed people must receive three doses of the vaccine according to the opinion of April 22, 2021 of the Vaccine Strategy Guidance Council. As a reminder, these are the people:

  • who have received an organ or hematopoietic stem cell transplant
  • under lymphopenic chemotherapy
  • treated with strong immunosuppressive drugs, such as antimetabolites (cellcept, myfortic, mycophenolate mofetil, imurel, azathioprine) and AntiCD20 (rituximab: Mabthera, Rixathon, Truxima)
  • chronic dialysis after the advice of your treating physician, who will decide on the need for appropriate tests;
  • case by case, people being treated with immunosuppressants that do not fall within the categories mentioned above or with primary immunodeficiency.
  • (as of June 18) with chronic lymphocytic leukemia or certain types of lymphoma treated with antiCD20.

During an interview with RTL, Jean Castex gave details on the schedule for the third dose, referring to a relaunch of the campaign in nursing homes on September 12 and 13. Those over 65 will be able to meet again “from the beginning of September,” adds the head of government, recalling that however a period of 6 months must be respected between the second and third dose. At the moment, this 3rd dose has not been extended to the entire population. A good decision for Alain Fischer, as he explains in an interview for Ouest France. We reserve it for people over 65 and people with chronic or obese diseases because the protection of the vaccine against severe forms of the disease tends to fade in the most fragile after six months. The reinforcement is justified for them, which represents 24 million people. the circulation of the virus remains contained, there is no reason at this stage to schedule a booster for everyone. It could be done quickly in case of rebounds, the immune memory can be easily awakened with a reminder, even long after the vaccine. “

On the other hand, HAS already indicated on October 7 that it recommended a 3rd dose for caregivers and those around them, a decision taken by the government.

Black cohosh, this 3rd dose is necessary for caregivers according to Mr. Vaccine of the government Alain Fischer “because they are more exposed than others by their work, and because the fantastic increase in antibodies induced by the third dose makes the is likely that the disease is transmitted less. Both arguments support the withdrawal. “

As for the current vaccination, you can schedule an appointment on dedicated platforms like Doctolib, which starts scheduling an appointment on Monday, August 30 for the first injections scheduled for September 1. You can also make an appointment with your doctor or the nearest pharmacy.

For nursing homes, it is on a specific platform where structures can request the vaccine two days a week. For the organization, the nursing home officials estimate that two nurses and four caregivers, for two or three days, are enough to care for a hundred residents.

A study conducted by the Maccabi health insurance organization in Israel shows that one third of the Pfizer vaccine would be 86% effective for people over 60 years of age. The study compared the results seen in 149,144 people over the age of 60 at least one week after receiving a booster shot, with those of another 675,630 who had only received two doses in January or February. According to the study, 37 of those who received a third injection tested positive for the coronavirus, or 0.24 per 1,000, compared with 1,064 among those who received just two doses, or 1.57 per 1,000. As a reminder, Pfizer and BioNTech had said in a press release that this recall allowed “to preserve and even exceed the high levels of protection against the original strain of the coronavirus responsible for Covid and against its variants,” according to data from their trial from phase 1.

Should we be afraid of it? According to an American study, published on Tuesday, September 28, the first studies in people who received a third dose are quite positive to date. “Currently, booster doses are well tolerated,” said the CDC (Centers for Disease Control and Prevention). If any side effects were detected, they will still be very similar to those seen during the second injection.

In fact, of the 20,000 people observed, 79% reported localized pain, particularly at the site of the bite, and 74% confirmed the presence of a “systemic” reaction, for example, fatigue. “The frequency and type of side effects were similar to those seen after the second dose of the vaccine, and were mostly mild or moderate and of short duration,” said Rochelle Walensky, director of the CDC, at a conference on press.

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