COVID-19

COVID-19. Efficacy, Side Effects, Timing – Everything You Need To Know About The Third Dose Of The Vaccine

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The High Health Authority is in favor of a third dose of vaccine against Covid-19 for people over 40 years of age. A booster of the vaccine that would increase the protection of the patients against the virus. Here is what you need to know.

Never two without three. While only those over the age of 65 are currently authorized to receive a booster dose of the Covid-19 vaccine, vaccination will expand. Those over 50 will soon have access to it. People over 40 should also receive a third dose of Covid-19 vaccine, estimates the High Health Authority. Opinion on which the government has not yet ruled.

  • Is the third dose effective?

The third dose of the Covid-19 vaccine would provide strong protection for the patient, according to a paper published in The Lancet on October 29. A study was conducted in Israel in 1.4 million people with a group of patients who had received the second dose at least five months ago and a group of patients vaccinated for the third time. The third dose was 93% effective against hospitalization, 92% against very severe forms of the disease, and 81% against risk of death.

The third dose brings “an extremely strong immune reaction in 48 hours unlike the first two,” explained the president of the Scientific Council. An immune response “about ten times stronger than after the second dose,” explained Professor Jean-François Delfraissy in France Inter on Wednesday. The impact of the bite seems to appear from the seventh day.

An immune response “10 times stronger than after the 2nd dose”, which appears “in the 48 hours after the injection”, but “we do not know if it will last in time”, summarizes Jean-François Delfraissy.

The impressive boost of the third dose u23e9https: //t.co/UzckKt3t32 pic.twitter.com/U5R4bpliPn

– Nicolas Berrod (@nicolasberrod) November 18, 2021

How long does this third dose protect the patient? Hard to say. Will the protection be longer than after the first two injections? Israeli researchers from Tel Hashomer Hospital, cited by The Times of Israel, cite a duration of nine to ten months. The next few months will allow us to know and decide if an annual vaccination against both the virus and the flu is necessary.

  • Are there any side effects?

With the Pfizer vaccine or the Moderna vaccine, “no specific signs were identified in people who had a booster dose,” indicates the ANSM pharmacovigilance report. The reported side effects are similar to those of the first two doses. The National Agency for Drug Safety recorded the death of 26 patients who received a booster vaccination with Pfizer and 3 with Moderna. “Older people, mostly residents in nursing homes or nursing homes and who have serious comorbidities,” details the ANSM. And add that “nothing allows us to conclude that these deaths are related to the vaccine.”

  • What vaccines are used for the third dose?

The vaccine booster is performed only with a messenger RNA vaccine (Pfizer-BioNTech or Moderna) regardless of the vaccine or vaccines used for the first two doses. The injection should be done six months after the full vaccination schedule for patients vaccinated with Pfizer-BioNTech, Moderna, or AstraZenecca and 1 month for Janssen.

  • Will all adults ever need to be vaccinated?

Those over 65 and the most fragile receive the third dose from the beginning of September. 5,247,811 people received a booster dose, as of November 19, according to the Ministry of Health. Those over 50 can, in turn, be vaccinated again as of December 1. On Friday, the High Health Authority gave the green light to vaccinate people over 40 years of age. This opinion has not yet been validated by the government.

Also read: Covid-19: a vaccine booster after 40 years recommended by the High Health Authority

Will we finally move towards vaccinating people over 18 with a third dose? Professor Jean-François Delfraissy, President of the Scientific Council, wishes it. “Most likely we will receive a third dose in the general population,” he told France Inter on Wednesday. Emmanuel Macron, for his part, does not say no. “If it turns out that a third dose is effective and necessary for other audiences, obviously, we will integrate it into the logic of the past,” said the head of state at La Voix du Nord on Friday.

Also read: Covid-19: booster dose, mask, fifth wave … What to remember from the interview with Jean-François Delfraissy, president of the scientific council

  • Where to do your third dose?

Several vaccination sites are authorized to perform the third injection: vaccination centers, your treating doctor, a nurse, a midwife, a pharmacy or a medical biology laboratory. The list of vaccination sites is available on the website sante.fr.

A third mandatory dose for the health pass.

To keep their health pass active, starting December 15, people 65 and older must receive their Covid-19 vaccine booster. A period of at least six months is granted after the second dose and a maximum of four additional weeks. Beyond that, the QR code on the health pass will be automatically deactivated. For patients vaccinated with Janssen, the single-dose vaccine, the delay is not six months, but one month.

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