Covid vaccines: a list of side effects identified in France

Posted by Cecile D. Posted on July 20, 2021 at 1:16 PM Updated on July 20, 2021 at 1:17 PM

Vaccinations continue in France and health authorities are still closely monitoring the various vaccines in circulation. Here is a list of side effects reported in France.

number Business date, meeting the number of people taken for the first dose of Covid-19 vaccine continues to rise. In France, there are about 37 million first injection doses and 30 million people are fully vaccinated. At the level around the world, 3.6 billion doses have been administered and over a billion people are immune.

After months of observation and analysis, the health authorities were able to draw up a list of Side effects sufficiently accurate and complex vaccines.

INNational Agency for the Safety of Medicines Therefore, on July 16, 2021, a report was drawn up listing all the side effects of the vaccines reported by the French. Pfizer, AstraZeneca, Moderna and Janssen : All vaccines approved in France have been analyzed.

In this report, ANSM explains that it conducted a national vaccination study in France. The agency bases its analysis on more than 59 165 000 injections held on July 8, 2021, including:

  • “More than 45,779,000 injections with COMIRNATY (BioNTech-Pfizer)
  • More than 5 566 000 SPIKEVAX (Moderna) injections
  • Over 720,000 VAXZEVRIA (AstraZeneca) injections
  • More than 609,000 injections of COVID-19 Janssen vaccine “

Since the start of the vaccination campaign in France, more than 61,800 side effects have been reported with all vaccines. Only a quarter of them were found to be serious.

Side effects frivolous and often, regardless of the vaccine administered, the following have been identified:

  • Tired
  • Pain at the vaccination site
  • Muscle or joint pain
  • Limb pain
  • Swollen lymph nodes
  • Rash, itching
  • Heat
  • Headache
  • Nausea
  • Vomiting
  • Dizziness


The Pfizer vaccine study shows similar proportions: 28% of cases were considered serious. In adolescents, as in adults, the same effects and signals were revealed.

Side effects of Pfizer that have been observed include:

  • Shingles
  • Heart rhythm disorders
  • Thrombocytopenia / Immunological Thrombocytopenia / Spontaneous Hematomas
  • Diabetic imbalance in the context of reactogenicity
  • Vaccine failures
  • Acute pancreatitis
  • Guillain-Barré Syndromes
  • Macrophage Activation Syndrome
  • Epstein-Barr virus reactivation
  • Zosterian meningoencephalitis
  • Idiopathic aplastic anemia
  • Acquired hemophilia
  • Arterial hypertension
  • Myocarditis (64 cases) and pericarditis (111 cases)
  • Rheumatoid arthritis (22 severe cases since vaccination initiation, 15 of which had a history of arthritis)
  • Glomerular nephropathy, which is the so-calledkidney ruble (12 cases since the beginning of vaccination, of which 8 relapses)

Most of these severe cases have been seen in people with more than 50 years

Three major events are reported in pregnant or lactating women vaccinated by Pfizer:

  • Death in the womb: Since the beginning of the follow-up, there have been 3 deaths in the womb following the Komirnati vaccination. No link to vaccination can be established. Death in the womb occurs between 1 and 3 pregnancies per 1000 in the general population.
  • Thromboembolic events
  • Painful contractions of the uterus


Observed side effects:

  • Rheumatoid arthritis (RA): 3 severe cases, including one positive re-injection.
  • Glomerular nephropathies: 3 cases of glomerular nephropathies, including 2 positive re-dosing after dose 2 and one case after dose 2. These cases occurred in patients aged 20 to 80 years, all within a short period of time (<2 days).
  • Skin bleeding of the mucous membranes (menstrual irregularities): 15 severe cases. In the absence of further assessment of reported cases, it is impossible to foresee the role of the vaccine in their occurrence.
  • Erythema multiforme: 2 cases of erythema multiforme, including one with a confirmed diagnosis. There is no evidence of serious skin damage that would compromise the benefit / risk ratio of the vaccine.
  • Rhythm disturbances
  • Shingles
  • More pronounced reactogenicity after 2nd dose
  • Imbalance / recurrence of chronic pathologies
  • Amnesic attack (transient amnesia)
  • Hearing problems (deafness, hearing loss, and tinnitus)
  • Loss of knowledge, more or less related to falls
  • Delayed reactions: These reactions, well documented in vaccine clinical trials, are mostly non-serious and occur on average within 4–31 days after vaccination.
  • Vascular diseases such as arterial hypertension.
  • Myocarditis (7 cases) and pericarditis (13 cases)


Observed side effects:

  • Mucocutaneous bleeding (mainly bruising and nosebleeds)
  • Shingles and herpetic reactivation
  • Increased blood pressure
  • Shortness of breath and asthma associated with flu-like syndromes
  • Acute polyradiculoneuritis (including Guillain-Barré syndrome)
  • Facial nerve palsy
  • Central demyelinating pathology
  • Erythema nodosum
  • Deafness and hearing loss
  • Ischemic colitis
  • Vasculitis
  • Myocarditis / pericarditis
  • Influenza-like syndromes: These are still the most commonly reported and new data collected confirms the results of previous weeks.
  • Thromboembolic Disorders: In order to harmonize French monitoring of thromboembolic disorders analyzed at a European level, it was decided to focus monitoring on the following events:
    • cerebral thrombosis
    • internal thrombosis
    • multipoint thrombosis
    • any thrombosis associated with thrombocytopenia
    • isolated internal combustion engines.

Faced with the risk of thrombosis, ANSM ” Recommends to anyone with persistent side effects for more than 3 days, such as dizziness, headache, visual disturbances, nausea / vomiting, shortness of breath, sharp pain in the chest, abdomen or limbs, or who have bruises on the skin (petechiae) outside the site vaccination, seek medical attention immediately… “


Observed side effects:

  • Thromboembolic events
  • Arterial hypertension
  • Guillain-Barré syndrome (4 cases)
  • Shingles
  • Myocarditis / pericarditis
  • Rare atypical thrombosis: occurs 4–28 days after vaccination and is characterized by:
    • Venous and / or arterial thrombosis (regardless of location) associated with a decrease in platelets (<150 g / L)
    • Venous and / or arterial thrombosis of unusual localization (localization, clinical context, possibly multiple sites, sometimes sequentially), in particular cerebral vein thrombosis and internal vein thrombosis.
  • Capillary Leak Syndrome: The effect has been reported worldwide, no cases have been reported in France to date

Generally, no serious side effects absolutely related to Covid-19 vaccines have not been found in France, among pregnant or lactating women… Very good news for young parents who may be worried about the consequences of this epidemic for their child or themselves.

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