The hydrogel dressing uses ultrasound to better adhere to the skin.

Sometimes it can be difficult to attach the bandage to the skin, especially if the skin is damp. However, this is not an issue with the new experimental bandage, which uses ultrasound-induced microbubbles to better adhere to the skin.

The dressing itself, developed by a team led by McGill University in Canada, is presented as a thin, transparent hydrogel sheet: it consists of polyacrylamide or poly(N-isopropylacrylamide) polymers, as well as a seaweed-derived alginate gel. . This hydrogel is combined with a liquid primer containing chitosan or gelatin nanoparticles or cellulose nanocrystals.

In any combination, after applying the primer and hydrogel to the wound, a small ultrasonic transducer is in contact with them. The ultrasonic waves travel through the hydrogel and cause the primer to cavitation, forming many microbubbles that push the primer molecules into the skin.

As a result, the bandage adheres to the skin much better than a traditional adhesive bandage: the higher the ultrasound intensity, the better the bandage adheres. And once the wound has healed, the bonding process can be reversed to remove the hydrogel.

Scheme illustrating the process of gluing the hydrogel to the skin.

Zhenwei Ma

In addition to being used to heal wounds, it is believed that this technology could also be used to deliver drugs through the skin… and the possibilities don’t stop there.

“By combining mechanics, materials and biomedical engineering, we envision a wide impact of our bioadhesive technology on wearable devices, wound care and regenerative medicine,” said lead researcher Professor Jianyu Li of McGill.

The journal recently published an article about a study that also involves scientists from the University of British Columbia and the Swiss ETH Zurich Institute. Sciences.

Font: McGill University

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